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[Bacteroides fragilis meningitis. 2 cases].

M Houvenaeghel, S de Moro, A Ottomani

    Presse Medicale (Paris, France : 1983)
    |October 4, 1986
    PubMed
    Summary
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    Bacteroides fragilis meningitis primarily affects the very young or elderly, often linked to contributing factors. Nitro-imidazole derivatives are the recommended treatment due to their effectiveness and cerebrospinal fluid penetration.

    Area of Science:

    • Infectious Diseases
    • Neurology
    • Microbiology

    Background:

    • Review of clinical and therapeutic features of meningitis caused by Bacteroides fragilis.
    • Analysis based on 2 personal cases and 23 literature cases.

    Observation:

    • Bacteroides fragilis meningitis predominantly affects the very young or elderly.
    • Contributing factors are present in 54% of cases.
    • Clinical presentation includes infectious syndrome, meningoencephalitis, and motor disorders.

    Findings:

    • Septicemia occurs in 80% of cases, yet general condition is moderately affected.
    • Elevated blood leucocyte counts and typical bacterial meningitis CSF disturbances are observed.
    • Initial infection focus identified in 60% of cases.

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  • Higher mortality rates in adults compared to children.
  • Frequent neurological complications are noted.

    • Implications:

    • Nitro-imidazole derivatives are the treatment of choice for Bacteroides fragilis meningitis.
    • High cerebrospinal fluid concentrations of nitro-imidazoles are crucial for effective treatment.
    • Understanding risk factors and clinical presentation aids in early diagnosis and management.