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Angiosarcoma of the Left Atrium: A Case Report

Georg Schlachtenberger1, Stephen Gerfer1, Axel Kröner1

  • 1Klinik und Poliklinik fur Herz- und Thoraxchirurgie, Klinikum der Universitat zu Köln, Köln, Germany.

The Thoracic and Cardiovascular Surgeon Reports
|February 24, 2018
PubMed

Insights

A rare cardiac angiosarcoma was diagnosed in a 76-year-old male. Despite surgical removal, the prognosis remains poor due to the tumor type and its resistance to standard treatments.

Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Primary cardiac tumors are rare, with benign types being more common.
  • Primary cardiac angiosarcoma represents a rare malignant entity within cardiac tumors.

Observation:

  • A 76-year-old male presented with a large cardiac tumor (8.6 × 5.6 cm) initially appearing benign on imaging.
  • The tumor was found to be adherent to the septum and left atrium.

Findings:

  • Pathological examination confirmed the cardiac tumor as an angiosarcoma.
  • Immunohistochemistry revealed ERG+ and CD31+/CD34+ expression, indicative of angiosarcoma.
  • Complete surgical resection was achieved via median sternotomy.

Implications:

  • Surgical resection is the primary treatment for cardiac tumors, but angiosarcoma carries a poor prognosis.
  • Angiosarcoma's poor response to chemotherapy and radiotherapy limits further treatment options.
  • This case highlights the diagnostic and therapeutic challenges of rare malignant cardiac tumors.

Keywords:
myxomasarcoma

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