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  1. Home
  2. Epic-coge: Managing And Analyzing Genomic Data.
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  2. Epic-coge: Managing And Analyzing Genomic Data.

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A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
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EPIC-CoGe: managing and analyzing genomic data.

Andrew D L Nelson1, Asher K Haug-Baltzell1, Sean Davey1

  • 1BIO5 Institute, School of Plant Sciences, University of Arizona, Tucson, AZ, USA.

Bioinformatics (Oxford, England)
|February 24, 2018

View abstract on PubMed

Summary
This summary is machine-generated.

The EPIC-CoGe browser offers a user-friendly, web-based platform for visualizing and analyzing genomic data. It integrates extensive genome databases with enhanced search and on-the-fly analysis features for researchers.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Genome visualization tools are crucial for interpreting complex genomic data.
  • Existing tools may lack comprehensive integration with large genome databases or advanced analytical capabilities.

Purpose of the Study:

  • To introduce the EPIC-CoGe browser, a novel web-based genome visualization utility.
  • To enhance genome data accessibility and analysis for researchers of all skill levels.

Main Methods:

  • Integration of the GMOD JBrowse genome browser with the CoGe genome database.
  • Development of enhanced search functionalities and on-the-fly comparative analysis tools.
  • Implementation of a user-friendly interface with a point-and-click wizard and REST API for data loading.

Main Results:

  • The EPIC-CoGe browser provides access to over 30,000 genomes.
  • It offers advanced features beyond basic JBrowse, including enhanced search and comparative genomics.
  • Data loading is simplified via a wizard or REST API, requiring no installation.

Conclusions:

  • EPIC-CoGe significantly improves accessibility and usability of large-scale genomic data.
  • The platform facilitates comparative genomics and functional analysis across diverse datasets.
  • Its embeddable nature allows integration into existing web resources and JBrowse instances.