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Related Experiment Videos

The Paredrine test in normal eyes. A controlled study.

K Heitman, D D Bodé

    Journal of Clinical Neuro-Ophthalmology
    |December 1, 1986
    PubMed
    Summary
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    Paredrine eye drops cause pupillary dilation in normal eyes, with faster responses in lighter irises. This study quantifies the pupillary response to Paredrine in healthy volunteers.

    Area of Science:

    • Ophthalmology
    • Pharmacology

    Background:

    • Paredrine is used in Horner's syndrome testing.
    • Controlled studies on pupillary response in normal eyes are lacking.

    Purpose of the Study:

    • To measure pupillary dilation in normal eyes after Paredrine instillation.
    • To document the time course and variability of the pupillary response.

    Main Methods:

    • Twenty-five volunteers with normal eye exams participated.
    • 1% Paredrine was administered to one eye, with the other serving as a control.
    • Serial photography documented pupillary size over time.

    Main Results:

    • Pupillary dilation occurred in the treated eye.
    • Eyes with lighter irises showed more rapid dilation.

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  • The control eye exhibited progressive constriction.

    • Conclusions:

    • Paredrine induces pupillary dilation in normal eyes.
    • Iris color influences the rate of dilation.
    • The study provides objective data on Paredrine's effect on pupil size.