Related Experiment Video
Updated: Feb 13, 2026

11:35
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
58.8K
Online meditation training for people with multiple sclerosis: A randomized controlled trial
Cesare Cavalera1, Marco Rovaris2, Laura Mendozzi2
1Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.
Summary
An online mindfulness-based intervention (MBI) improved quality of life and reduced psychological distress in multiple sclerosis (MS) patients short-term. However, these benefits did not last long-term, indicating a need for sustained support strategies.
Area of Science:
- Neurology
- Psychology
- Digital Health
Background:
- Multiple sclerosis (MS) significantly impacts patient quality of life (QOL) and increases psychological distress.
- Mindfulness-based interventions (MBIs) show promise, but logistical barriers can hinder participation.
- Online delivery of MBIs may overcome accessibility challenges for individuals with MS.
Purpose of the Study:
- To evaluate the effectiveness of an online MBI for improving QOL in MS patients.
- To assess the impact of an online MBI on psychological well-being, sleep, and fatigue.
- To determine the short-term and long-term effects of the intervention.
Main Methods:
- A randomized controlled trial involving 139 participants with MS.
- Assignment to either an MS-specific online MBI or an active control (psychoeducational) group.
- Assessment of QOL, depression, anxiety, sleep, and fatigue at baseline, 2 months, and 6 months.
Main Results:
- The online MBI group reported significantly higher QOL and lower depression, anxiety, and sleep problems at 2 months compared to the control group.
- These improvements were not sustained at the 6-month follow-up.
- No significant group differences were observed at the 6-month assessment.
Conclusions:
- Online MBIs may offer short-term psychological benefits for individuals with MS.
- The transient nature of the observed effects highlights the need for strategies to promote long-term well-being.
- Further research is required to develop sustainable interventions for MS management.
More Related Videos
Related Concept Videos
Trial and Error and Algorithm
430
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
430
Clinical Trials: Overview
5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
Clinical Trials
10.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.9K
Random Error
9.9K
Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
9.9K
Random Variables
17.9K
A random variable is a single numerical value that indicates the outcome of a procedure. The concept of random variables is fundamental to the probability theory and was introduced by a Russian mathematician, Pafnuty Chebyshev, in the mid-nineteenth century.
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
17.9K
Randomized Experiments
9.1K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
9.1K

