Related Experiment Video
Updated: Feb 13, 2026

07:54
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
7.3K
68Ga-DOTANOC PET/CT in Medulloblastoma
Clinical Nuclear Medicine
|February 28, 2018
Summary
This case study highlights a recurring desmoplastic medulloblastoma in a child. Ga-DOTANOC PET-CT revealed somatostatin receptor expression in the lesions, suggesting a new treatment avenue.
Area of Science:
- Pediatric neuro-oncology
- Molecular imaging in oncology
Background:
- Medulloblastoma is the most common pediatric posterior cranial fossa brain tumor.
- Desmoplastic medulloblastoma is a specific subtype with distinct characteristics.
Observation:
- A patient presented with recurrent desmoplastic medulloblastoma.
- Multiple recurrences of the tumor were noted.
Findings:
- Ga-DOTANOC PET-CT imaging demonstrated significant somatostatin receptor expression in the medulloblastoma lesions.
- This expression indicates potential for targeted therapy.
Implications:
- Somatostatin receptor expression offers a potential therapeutic target for recurrent medulloblastoma.
- Ga-DOTANOC PET-CT can identify patients who may benefit from somatostatin receptor-targeted therapies.
Related Concept Videos
Radiological Investigation I: X-ray and CT
1.2K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.2K
Imaging Studies I: CT and MRI
931
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
931
Imaging Studies for Cardiovascular System V: CT
383
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
383
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
527
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
527
Radiological Investigation III: Pulmonary Angiogram and PET Scan
487
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
487
Aggression
30.4K
Humans engage in aggression when they seek to cause harm or pain to another person. Aggression takes two forms depending on one’s motives: hostile or instrumental. Hostile aggression is motivated by feelings of anger with intent to cause pain; a fight in a bar with a stranger is an example of hostile aggression. In contrast, instrumental aggression is motivated by achieving a goal and does not necessarily involve intent to cause pain (Berkowitz, 1993); a contract killer who murders for...
30.4K

