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Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

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A Mouse Model of Intestinal Partial Obstruction
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Chronic Intestinal Pseudo-obstruction.

Khalil El-Chammas1, Manu R Sood2,3

  • 1Division of Pediatric Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Clinics in Colon and Rectal Surgery
|March 1, 2018
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Summary
This summary is machine-generated.

Chronic intestinal pseudo-obstruction (CIP) presents with bowel obstruction symptoms without a physical blockage. Early diagnosis and a multidisciplinary approach are key for managing this complex gastrointestinal disorder.

Keywords:
antroduodenal manometrybowel motilitychronic intestinal pseudo-obstruction

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Area of Science:

  • Gastroenterology
  • Gastrointestinal Motility Disorders

Background:

  • Chronic intestinal pseudo-obstruction (CIP) is a complex gastrointestinal disorder characterized by symptoms of bowel obstruction without a mechanical blockage.
  • It arises from intrinsic or extrinsic abnormalities affecting the enteric nervous system or smooth muscle of the bowel.
  • Nonspecific symptoms can lead to diagnostic delays.

Purpose of the Study:

  • To provide a comprehensive overview of Chronic Intestinal Pseudo-obstruction (CIP).
  • To outline diagnostic strategies and management principles for CIP.
  • To emphasize the importance of a multidisciplinary approach in patient care.

Main Methods:

  • Review of existing literature on CIP.
  • Discussion of diagnostic modalities including imaging, manometry, and histopathology.
  • Emphasis on a multidisciplinary team approach for management.

Main Results:

  • CIP is a heterogeneous group of disorders affecting bowel innervation and musculature.
  • Diagnostic workup involves imaging, manometry, and potentially biopsies.
  • Multidisciplinary management is crucial for optimizing nutritional status and managing pain.

Conclusions:

  • Effective management of CIP requires a coordinated, multidisciplinary team.
  • Treatment focuses on nutritional support, pain management, and preventing intestinal failure.
  • Small bowel transplantation is an option for refractory cases or complications.