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Analyte-Triggered DNA-Probe Release from a Triplex Molecular Beacon for Nanopore Sensing

Bingyuan Guo1,2,3, Yingying Sheng1, Ke Zhou2

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.

Angewandte Chemie (International Ed. in English)
|March 1, 2018
PubMed
Summary

Researchers developed a novel nanopore sensing strategy using triplex molecular beacons for detecting DNA and proteins. This method offers a sensitive, selective, and rapid tool for macromolecule detection, potentially aiding point-of-care diagnostics.

Keywords:
antibodiesbiomarkersmolecular beaconnanopore sensorsquantitative determination

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