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Updated: Feb 13, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Characterizing Cardiac Involvement in Chronic Kidney Disease Using CMR-a Systematic Review
Kenneth Mangion1, Kirsty McDowell1, Patrick B Mark1,2
11Institute of Cardiovascular and Medical Sciences, BHF Cardiovascular Research Centre, University of Glasgow, BHF Building, 126 University Place, Glasgow, G12 8TA UK.
Purpose Of Review:
The aim of the review was to identify and describe recent advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients with chronic kidney disease (CKD). We conducted a literature review in line with current guidelines.
Recent Findings:
The authors identified 22 studies. Patients with CKD had left ventricular global and regional dysfunction and adverse remodeling. Stress testing with CMR revealed a reduced stress-response in CKD patients. Native T1 relaxation times (as a surrogate markers of fibrosis) are elevated in CKD patients, proportional to disease duration. Patients with CKD have reduced strain magnitudes and reduced aortic distensibility.
Summary:
CMR has diagnostic utility to identify and characterize cardiac involvement in this patient group. A number of papers have described novel findings over the last 3 years, suggesting that CMR has potential to become more widely used in studies in this patient group.
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