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Published on: September 22, 2015
External Oxidant-Free Dehydrogenative Lactonization of 2-Arylbenzoic Acids via Visible-Light Photocatalysis
Ailong Shao1, Jirui Zhan1, Na Li1
1Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences , Wuhan University , Wuhan 430072 , Hubei , People's Republic of China.
Abstract:
An external oxidant-free C-H functionalization/C-O bond formation reaction for constructing benzo-3,4-coumarins accompanied by quantitative H2 evolution has been developed. High functional group tolerance and excellent reaction efficiency are shown in this transformation. Meanwhile, the substrates containing heterocyclic substituents such as thienyl-, pyridinyl-, and pyrrolylbenzoic acids displayed good performance. Importantly, this reaction can be performed with good efficiency on a gram scale. A cyclic voltammetry study and density functional theory calculations could provide insight into the mechanism of this reaction.
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