Related Experiment Video
Updated: Feb 13, 2026
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
Age-Related Prostate Specific Antigen Reference Ranges in Healthy Northern Iranian Men
Shahrzad Rahimifar1, Adel Montazeri
1Department of Laboratory Sciences, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Background:
Prostate cancer is the third most common malignancy in men worldwide. Despite being a helpful biomarker in prostate cancer, prostate specific antigen (PSA) is affected by different factors including age, lifestyle, geographical region and ethnicity.
Objective:
To determine the age specific serum PSA level among healthy Northern Iranian men and to compare the results of our study with the findings of other populations in the world.
Methods:
A total of 1271 men who were referred for routine check-up in a multispecialty hospital in the city of Rasht, in Northern Iran, were evaluated for their PSA levels by commercial ELISA method.
Results:
The normal age related prostate specific antigen range (0-95th percentile) in our study was 0.0-0.62 in men younger than 40 yrs; 0.0-0.75 ng/ml in 40-49 yrs; 0.0-0.91 ng/ml in 50-59 yrs; 0.0-1.33 ng/ml in 60-69 yrs; 0.0-1.45 ng/ml in 70-79 yrs group and 0.0-1.93 in subjects older than 80 yrs.
Conclusion:
The present study revealed the lowest upper limit of PSA level in all age groups in comparison to populations from different countries.
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