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Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes
Published on: February 8, 2018
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Full ocular biometry through dual-depth whole-eye optical coherence tomography
Hyung-Jin Kim1,2, Minji Kim1,2, Min Gyu Hyeon3
1Department of Bio-Convergence Engineering, Korea University, Anam-ro 145, Seongbuk-gu, Seoul 02841, South Korea.
Biomedical Optics Express
|March 20, 2018
Summary
This study introduces a novel dual-depth optical coherence tomography method to precisely measure the human eye's optical axis (OA), pupillary axis (PA), and visual axis (VA), crucial for refractive surgery.
Area of Science:
- Ophthalmology
- Biomedical Optics
- Medical Imaging
Background:
- Accurate determination of ocular axes is vital for ophthalmic applications, particularly refractive surgery.
- Existing methods may lack precision or comprehensive whole-eye imaging capabilities.
Purpose of the Study:
- To develop and validate a new dual-depth whole-eye optical coherence tomography (OCT) method for determining the optical axis (OA), pupillary axis (PA), and visual axis (VA).
- To assess the angles alpha (between OA and VA) and kappa (between PA and VA).
Main Methods:
- Utilizing dual-depth whole-eye OCT to reconstruct complete eye images from simultaneous anterior segment and retinal scans.
- Employing orthogonal polarization components for distinct imaging of the anterior segment and retina.
- Identifying OA and PA geometrically from anterior segment images; detecting VA via cross-correlation between anterior and retinal images.
Main Results:
- The proposed method successfully determines the OA, PA, and VA using whole-eye OCT.
- Feasibility demonstrated in both a model eye and human subjects.
- Angles alpha and kappa can be accurately calculated.
Conclusions:
- Dual-depth whole-eye OCT offers a robust approach for precise ocular axis measurement.
- This technique has significant potential for enhancing accuracy in refractive surgery planning and execution.
Keywords:
(110.4500) Optical coherence tomography(170.3880) Medical and biological imaging(170.4470) Ophthalmology(170.4500) Optical coherence tomographyMore Related Videos
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