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Physiological Recording in the MRI Environment (PRiME): MRI-Compatible Hemodynamic Recording System
John W Kakareka1, Anthony Z Faranesh2, Randall H Pursley1
1National Institutes of HealthBethesdaMD20892USA.
Summary
This study developed a novel system to reduce electromagnetic interference (EMI) during MRI-guided cardiovascular interventions. The system successfully minimized noise in electrocardiogram (ECG) and invasive blood pressure (IBP) signals, enabling clearer hemodynamic recordings.
Area of Science:
- Cardiovascular Interventions
- Medical Imaging
- Biomedical Engineering
Background:
- Hemodynamic monitoring is crucial for cardiovascular interventions.
- Magnetic Resonance Imaging (MRI) offers potential for guided procedures.
- Electromagnetic interference (EMI) in MRI environments corrupts hemodynamic signals.
Purpose of the Study:
- To develop and validate a system for minimizing EMI on electrocardiogram (ECG) and invasive blood pressure (IBP) signals during MRI.
- To enable high-fidelity hemodynamic recording in MRI-guided cardiovascular procedures.
Main Methods:
- Developed a system with MRI-compatible leads, custom electronics, and adaptive signal processing.
- Tested the system on pediatric patients during real-time, gradient-intensive MRI-guided catheterization.
- Quantified EMI reduction by measuring noise peaks and false QRS triggers.
Main Results:
- Achieved an 80% reduction in peak noise amplitude during gradient-intensive MRI sequences.
- Reduced false QRS triggers to a median of 0.
- Observed no detectable interference on invasive blood pressure (IBP) channels.
Conclusions:
- Successfully developed and deployed a hemodynamic recording system front-end for MRI environments.
- The system enables high-fidelity ECG and IBP recording during MRI scanning.
- Publicly available schematics facilitate broader implementation for MRI-guided interventions.
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