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Porcine Model of Infrarenal Abdominal Aortic Aneurysm
Published on: November 21, 2019
Accuracy of Routine Endoscopy Diagnosing Colonic Ischaemia After Abdominal Aortic Aneurysm Repair: A Meta-analysis
Gerdine C I von Meijenfeldt1, Tryfon Vainas2, Georgios A Mistriotis2
1Department of Surgery (Division of Vascular Surgery), University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Routine endoscopy accurately rules out colonic ischaemia (CI) after abdominal aortic aneurysm (AAA) surgery. However, it is less effective for diagnosing severe transmural CI, though it remains a safe procedure.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Diagnostic Accuracy Studies
Background:
- Colonic ischaemia (CI) is a serious complication following abdominal aortic aneurysm (AAA) surgery.
- Accurate diagnosis of CI is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the diagnostic test accuracy of routine endoscopy in diagnosing CI after elective and acute AAA repair.
Main Methods:
- Systematic review and meta-analysis of prospective studies.
- Searched Pubmed and Embase databases for relevant literature.
- Assessed study quality using QUADAS-2 tool and calculated diagnostic odds ratios.
Main Results:
- Included 12 studies with 718 AAA patients; 20.8% had CI, and 6.5% had Grade 3 CI.
- Endoscopy showed a pooled diagnostic odds ratio of 26.60 for all CI grades.
- Sensitivity for Grade 3 CI was 0.52, specificity was 0.97, with high post-test probabilities.
Conclusions:
- Routine endoscopy is highly accurate for excluding CI post-AAA repair.
- Endoscopy has limitations in diagnosing transmural CI but is a safe diagnostic tool.
- Clinicians should consider endoscopy's accuracy limitations for severe CI.
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