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Updated: Feb 13, 2026

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
Published on: August 2, 2012
Supramolecular Polymerization of [5]Helicenes. Consequences of Self-Assembly on Configurational Stability
Jorge S Valera1, Rafael Gómez1, Luis Sánchez1
1Departamento de Química Orgánica I, Facultad de Ciencias Químicas , Universidad Complutense de Madrid , 28040 Madrid , Spain.
Abstract:
The supramolecular polymerization of [5]helicenes 1 and 2 is investigated. The self-assembly of these helicenes proceeds by the operation of H-bonding interactions with a negligible participation of π-stacking. The enantiopurity of the sample has a dramatic effect on the supramolecular polymerization mechanism since it reverts the isodesmic mechanism for the racemic mixture to a cooperative one for the enantioenriched sample. Noticeably, the formation of supramolecular polymers efficiently increases the configurational stability of 1,14-unsubstituted [5]helicenes.
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