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Published on: September 27, 2017
[Topical ozone application: An innovative therapy for infantile atopic dermatitis]
Guizhi Qin1, Jinhua Huang2, Yizhi Pan2
1Department of Dermatology, Longhua Distric Central Hospital of Shenzhen, Shenzhen Guangdong 518110, China.
Objective:
To evaluate the clinical efficacy and safety of the innovative topical ozone therapy for infantile atopic dermatitis. Methods: Sixty children with atopic dermatitis were divided into a treatment group and a control group. The treatment group was showered with ozonated water (3-5 times a week) and smeared with ozonated oil (twice a day), while the control group was washed with warm running water and smeared with base oil, adding moisturizer if necessary. The treatment course was 2 weeks. Efficacy and side effect were evaluated. Results: The skin exudation was reduced and erosion was healing after 3-5 days topical ozone therapy for infantile atopic dermatitis. The effective rates were 80.0% and 20.0% in the treatment group and control group for 1 week, and 89.6% and 30.7% for 2 weeks, respectively, with significant difference between the 2 groups (P<0. 001). Conclusion: Innovative treatment of infantile atopic dermatitis with topical ozone application is safe and effective, which is worth popularizing in clinic.
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