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Updated: Feb 13, 2026

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF ACUTE MACULAR NEURORETINOPATHY REVEALS DEEP CAPILLARY ISCHEMIA
Julia Nemiroff1, David Sarraf2,3, Juan Pablo Davila2
1East Florida Eye Institute, Stuart, Florida.
Purpose:
To present the multimodal retinal imaging findings, including optical coherence tomography (OCT) angiography, of an atypical case of acute macular neuroretinopathy (AMN).
Methods:
The multimodal retinal imaging findings, including structural OCT and OCT angiography, of an atypical case of AMN are presented.
Results:
A 23-year old woman, with a history of an unrelenting sinusitis treated with prednisone therapy and decongestants, presented with an acute scotoma of the right eye. Structural OCT illustrated an area of hyperreflectivity in the outer plexiform and outer nuclear layers nasal to the fovea, with associated disruption of the inner segment ellipsoid band consistent with AMN. At the 2-week follow-up visit, intraretinal fluid was noted with repeat OCT, with spontaneous resolution of the fluid at the 2-month follow-up visit. Optical coherence tomography angiography illustrated a flow void in the deep retinal capillary plexus associated with the AMN lesion.
Conclusion:
Atypical findings of AMN are presented in this case report including the presence and spontaneous resolution of intraretinal fluid. Although OCT angiography illustrated a flow deficit within the deep retinal capillary plexus, the cause of AMN remains elusive.
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