Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Crystallography02:18

X-ray Crystallography

26.3K
The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
26.3K
X-ray Imaging01:24

X-ray Imaging

10.6K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
10.6K
X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

4.9K
X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
4.9K
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

1.2K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.2K
Mnemonic Devices01:23

Mnemonic Devices

445
Mnemonic devices are cognitive tools that facilitate memory retention by linking new information to familiar patterns or organizational strategies. These techniques are beneficial for remembering complex or lengthy sets of information by simplifying and structuring them in easily retrievable ways.
Acronyms
Acronyms are created by using the initial letters of a series of words to form a new word or phrase. This approach condenses complex information into a single, memorable entity. For example,...
445
Non-ohmic Devices00:51

Non-ohmic Devices

1.5K
In most substances, the current flow is proportional to the voltage applied to it. A simple relationship between the values of current, voltage, and resistance is known as Ohm's law. Nonohmic devices do not exhibit a linear relationship between voltage and current. One such device is the semiconducting circuit element known as a diode. A diode is a circuit device that allows current flow in only one direction.
Consider a simple circuit consisting of a battery, a diode, and a resistor. A...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Guest Editorial: next-generation analytical systems: devices and software.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026
Same author

Mechanistic Insights into Oxygen Release from Layered Oxide Cathodes for Reliable Sodium-Ion Batteries.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Synchrotron x-ray diffraction study of liquid and glassy toluene.

The Journal of chemical physics·2026
Same author

Flow-programmable and reversible surface-induced LLPS in nanofluidic channels.

Lab on a chip·2026
Same author

Association Between Distal Stent Retriever Deployment Distance and First-Pass Effect and Hemorrhagic Complications in Combined Thrombectomy.

AJNR. American journal of neuroradiology·2026
Same author

WebPDF: a browser-based software application for calculating X-ray pair distribution function.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
See all related articles

Related Experiment Video

Updated: Feb 12, 2026

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics
07:23

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics

Published on: February 5, 2020

6.2K

Nano X-ray diffractometry device for nanofluidics.

Kazuma Mawatari1, Hiroki Koreeda, Koji Ohara

  • 1Department of Applied Chemistry, School of Engineering, The University of Tokyo, Tokyo, Japan. kmawatari@icl.t.u-tokyo.ac.jp.

Lab on a Chip
|March 30, 2018
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel nanofluidic device enabling X-ray diffractometry for analyzing nanochannel water structure. This breakthrough allows studying liquid behavior in nanospaces, crucial for nanoscale chemistry and biology.

More Related Videos

Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis
08:26

Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis

Published on: December 10, 2019

10.0K
Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
10:39

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

10.1K

Related Experiment Videos

Last Updated: Feb 12, 2026

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics
07:23

Fabrication of Nanoheight Channels Incorporating Surface Acoustic Wave Actuation via Lithium Niobate for Acoustic Nanofluidics

Published on: February 5, 2020

6.2K
Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis
08:26

Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis

Published on: December 10, 2019

10.0K
Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
10:39

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

10.1K

Area of Science:

  • Physics
  • Materials Science
  • Chemistry

Background:

  • Nanofluidics exhibits unique properties distinct from microfluidics as channel size decreases below 500-800 nm.
  • Understanding microscopic liquid structure is key to explaining these phenomena, but nanochannel volumes hinder traditional analysis.

Purpose of the Study:

  • To develop a novel nanofluidic device for X-ray diffractometry analysis of confined water structure.
  • To overcome the limitations of small sample volumes and large substrate interference in nanochannel analysis.

Main Methods:

  • Fabrication of a specialized nanofluidic device using top-down and bottom-up processes.
  • Significant reduction of substrate thickness to 2.7 μm in the measurement area.
  • Application of X-ray diffractometry to analyze water confined within 500 nm nanochannels.

Main Results:

  • Successful observation of clear X-ray diffraction signals from water within nanochannels.
  • Calculation of the radial distribution function, indicating a structure similar to bulk water.
  • Demonstration of the feasibility of X-ray diffractometry for nanochannel analysis.

Conclusions:

  • The developed nanofluidic device enables direct structural analysis of liquids in nanospaces using X-ray diffractometry.
  • This technique provides critical insights into nanoscale liquid behavior, impacting chemistry and biology.
  • Facilitates the design of advanced chemical reactions and fluidic circuits for highly functional nanoscale devices.