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[Contact allergy to the antifungal agent naftifin]
E Hoting1, B Küchmeister, B M Hausen
1Allergie-Abteilung, Universitäts-Hautklinik, Hamburg.
Abstract:
Two patients treated topically against dermatophytes with a naftifine containing antifungal became allergic to the efficacious component naftifine. One of them also reacted to benzyl alcohol. Sensitization experiments in guinea pigs corroborated the suspicion that this allylamine is a contact sensitizer. To date, only few cases of allergic reactions to naftifine have been reported.