Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

What are Second Messengers?

What are Second Messengers?

Because many receptor binding ligands are hydrophilic, they do not cross the cell membrane and thus their message must be relayed to a second messenger on the inside. There are several second messenger pathways, each with their own way of relaying information. G-protein coupled receptors can activate both phosphoinositol and cyclic AMP (cAMP) second messenger pathways. The phosphoinositol path is active when the receptor induces phospholipase C to hydrolyze the phospholipid,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Medical termination of unplanned pregnancies in women with diabetes.

JPMA. The Journal of the Pakistan Medical Association·2025

Same author

Gonadal guardianship-ergonomic endocrinology.

JPMA. The Journal of the Pakistan Medical Association..·2025

Same author

Socionutrition: The science of socionutrients.

JPMA. The Journal of the Pakistan Medical Association·2025

Same author

The International Evidence-based Guidelines for the Assessment and Management of Polycystic Ovary Syndrome: An Exemplar of Person-centred Care.

TouchREVIEWS in endocrinology·2024

Same author

Ultra Processed Foods: A South Asian culinary perspective.

JPMA. The Journal of the Pakistan Medical Association·2024

Same author

Functional Foods may be Dysfunctional: A South Asian Perspective.

JPMA. The Journal of the Pakistan Medical Association·2024

Same journal

Domestic Violence - Are Women Safe Now? A Comparison between Nationwide Surveys of India.

Journal of mid-life health·2026

Same journal

Uterine Leiomyosarcoma in a Case of Leiomyoma: A Rare Encounter with Review of Newer Diagnostic Modalities.

Journal of mid-life health·2026

Same journal

Association of Vasomotor Symptoms and Cardiac Autonomic Functions in Perimenopausal Women.

Journal of mid-life health·2026

Same journal

Efficacy of <i>Shankhapushpi</i> (<i>Convolvulus pluricaulis</i>) in Posthysterectomy Menopausal Syndrome - A Randomized Controlled Pilot Clinical Trial.

Journal of mid-life health·2026

Same journal

Accuracy of Magnetic Resonance Imaging in Staging Endometrial Cancer: A Retrospective Single-center Observational Study.

Journal of mid-life health·2026

Same journal

Obesitogenic Hypothyroidism: Diagnostic Challenges and Therapeutic Implications in Modern Endocrinology.

Journal of mid-life health·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 12, 2026

Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry

Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry

Published on: August 13, 2021

Inositols in Midlife.

Sanjay Kalra¹, Bharti Kalra²

¹Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.

Journal of Mid-Life Health

|April 10, 2018

Summary

This summary is machine-generated.

Inositols, including myo-inositol and D-chiro-inositol, show promise for improving metabolic health in postmenopausal women. This review examines mechanistic, animal, and clinical data supporting their use.

Keywords:

D-chiro-inositol Diabetes metabolic syndrome myo-inositol postmenopausal

More Related Videos

Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC

Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC

Published on: June 26, 2020

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

Related Experiment Videos

Last Updated: Feb 12, 2026

Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry

Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry

Published on: August 13, 2021

Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC

Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC

Published on: June 26, 2020

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

Area of Science:

Biochemistry
Pharmaceutical Science
Genetics
Metabolic Health

Background:

Metabolic syndrome is a growing concern in postmenopausal women.
Inositols are naturally occurring compounds with potential health benefits.
Understanding the role of inositols in metabolic health is crucial.

Purpose of the Study:

To review mechanistic, animal, and clinical data on inositols in midlife women.
To explore the mechanism of action of myo-inositol and D-chiro-inositol.
To assess the potential of inositols for maintaining metabolic health in postmenopausal women.

Main Methods:

Review of mechanistic studies on inositol.
Analysis of animal studies on inositol in nephropathy and related conditions.
Examination of randomized controlled trials in postmenopausal women with metabolic syndrome.

Main Results:

Myo-inositol and D-chiro-inositol exhibit specific mechanisms of action.
In vitro and animal studies support the role of inositols in related conditions.
Clinical trials indicate potential benefits for metabolic health in postmenopausal women.

Conclusions:

Inositols demonstrate a potential role in managing metabolic health.
Further research into inositol supplementation for postmenopausal women is warranted.
Advances in biochemistry, pharmaceutical science, and genetics inform the understanding of inositol's effects.