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Abigail L Walling, Hobart W Walling1

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Phytophotodermatitis, a skin reaction, occurs after contact with phototoxic plants like wild parsnip and UV light exposure. This case highlights the risk of blistering and hyperpigmentation from this invasive weed.

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Area of Science:

  • Dermatology
  • Botany
  • Toxicology

Background:

  • Phytophotodermatitis is a skin reaction caused by UV light exposure after contact with phototoxic compounds.
  • Wild parsnip (Pastinaca sativa) is an invasive Umbelliferae family plant containing furocoumarins.

Observation:

  • A woman developed phytophotodermatitis after encountering wild parsnip on a midwestern prairie.
  • The plant's stems and leaves contain furocoumarins, which are activated by UV light.

Findings:

  • UV-activated furocoumarins interact with oxygen, producing reactive oxygen species.
  • These reactive oxygen species cause tissue damage, leading to blistering and hyperpigmentation.

Implications:

  • Increased prevalence of wild parsnip in North American prairies poses a public health risk.
  • Awareness of wild parsnip's phototoxic properties is crucial for preventing phytophotodermatitis.