Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise Stress Test01:26

Exercise Stress Test

1.4K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.4K
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

2.5K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.5K
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

2.0K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
2.0K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

4.5K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
4.5K
Testes: Histology01:27

Testes: Histology

3.1K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
3.1K
Complementation Tests00:49

Complementation Tests

6.3K
A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.

The Lancet. Respiratory medicine·2026
Same author

From mild-to-moderate to severe asthma: Risk factors and patient profiles from the NORDSTAR cohort.

American journal of respiratory and critical care medicine·2026
Same author

Azithromycin enhances epithelial antiviral immunity in uncontrolled asthma: results from the AZIMUNE randomized controlled trial.

The European respiratory journal·2026
Same author

Five-year inhaled, systemic, and total corticosteroid exposure reduction during anti‒interleukin-5 receptor alpha treatment for severe asthma.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same author

Dupilumab for Chronic Spontaneous Urticaria with Comorbid Type 2 Inflammatory Conditions: Case Report and Systematic Review of the Literature.

Case reports in dermatology·2026
Same author

Cumulative corticosteroid burden over 25 years in patients initiating biologic therapy for severe asthma: a nationwide cohort study.

ERJ open research·2026
Same journal

Anaphylaxis: State-of-the-Art.

Immunology and allergy clinics of North America·2026
Same journal

Upending Impending Doom.

Immunology and allergy clinics of North America·2026
Same journal

Mast Cell Activation Syndrome and Mimickers.

Immunology and allergy clinics of North America·2026
Same journal

Hereditary Alpha-Tryptasemia (HαT) as a Risk Modifier for Severe Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same journal

Emerging Therapies for Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same journal

Novel Epinephrine Delivery Devices.

Immunology and allergy clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Feb 12, 2026

A Swimming-Induced Zebrafish Exercise Apparatus for Versatile Training Approaches
10:34

A Swimming-Induced Zebrafish Exercise Apparatus for Versatile Training Approaches

Published on: October 18, 2024

1.9K

Testing for Exercise-Induced Bronchoconstriction.

John D Brannan1, Celeste Porsbjerg2

  • 1Department of Respiratory and Sleep Medicine, John Hunter Hospital, Lookout Road, New Lambton, New South Wales 2305, Australia.

Immunology and Allergy Clinics of North America
|April 11, 2018
PubMed
Summary
This summary is machine-generated.

Exercise-induced bronchoconstriction (EIB) is a treatable condition in asthma patients. Objective testing, including surrogate tests like inhaled mannitol, helps identify individuals at risk during physical activity.

Keywords:
Airway hyperresponsivenessEucapnic voluntary hyperpneaExercise-induced bronchoconstrictionMannitol

More Related Videos

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

21.4K
Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS
04:53

Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS

Published on: May 27, 2018

7.9K

Related Experiment Videos

Last Updated: Feb 12, 2026

A Swimming-Induced Zebrafish Exercise Apparatus for Versatile Training Approaches
10:34

A Swimming-Induced Zebrafish Exercise Apparatus for Versatile Training Approaches

Published on: October 18, 2024

1.9K
Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

21.4K
Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS
04:53

Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS

Published on: May 27, 2018

7.9K

Area of Science:

  • Pulmonology
  • Sports Medicine
  • Allergy and Immunology

Background:

  • Exercise-induced bronchoconstriction (EIB) signifies active, treatable airway hyperresponsiveness in individuals with asthma.
  • EIB can manifest with or without current asthma symptoms.
  • Identifying EIB is crucial for individuals engaging in sports or occupational physical activities.

Purpose of the Study:

  • To highlight the significance of objective EIB documentation.
  • To discuss diagnostic methods for EIB, including laboratory exercise testing and surrogate tests.
  • To emphasize the diagnostic advantages of surrogate tests.

Main Methods:

  • Review of diagnostic approaches for EIB.
  • Comparison of laboratory exercise testing with surrogate tests such as eucapnic voluntary hyperpnea and osmotic stimuli (inhaled mannitol).

Main Results:

  • Objective documentation of EIB aids in identifying at-risk individuals.
  • Surrogate tests, including inhaled mannitol, demonstrate improved diagnostic sensitivity for EIB.
  • Surrogate tests offer enhanced standardization compared to laboratory exercise testing.

Conclusions:

  • EIB is a key indicator of treatable pathophysiology in asthma.
  • Surrogate tests provide a more sensitive and standardized method for diagnosing EIB.
  • Objective EIB diagnosis is vital for safety during physical exertion.