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Tube patency: Is there a difference following otic drop administration?
1Resonance and Swallowing Center Professor of Otolaryngology, University of Pittsburgh School of Medicine, 4401 Penn Ave., Pittsburgh, PA 15224, United States.
American Journal of Otolaryngology
|April 11, 2018
Summary
This study found that not using peri-operative otic drops did not increase tympanostomy tube occlusion rates. Tube patency remained high, suggesting otorrhea is the primary cause of blockage.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Pharmacology
Background:
- Peri-operative otic drops are commonly used to maintain tympanostomy tube patency.
- The efficacy of routine otic drop use versus alternative methods is not fully established.
Purpose of the Study:
- To evaluate tympanostomy tube patency in patients who did and did not receive peri-operative otic drops.
- To assess the impact of a one-time administration of ciprofloxacin (OTO-201) as an alternative to otic drops.
Main Methods:
- A post-hoc analysis of three randomized, controlled trials involving 591 pediatric patients.
- Patients received either placebo/sham or OTO-201, with otic drops administered if otorrhea occurred.
- Tube patency was assessed via pneumatic otoscopy and tympanometry over 28 days.
Main Results:
- Tube patency rates were high in both groups, ranging from 87-95% with otic drops and 96-99% without.
- No significant increase in tube occlusion was observed in patients who did not receive otic drops.
Conclusions:
- Tympanostomy tube occlusion rates were not increased in patients not receiving peri-operative otic drops.
- Peri-operative otorrhea appears to be the primary factor influencing tube occlusion, as patency approached 99% when this complication was absent.
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