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Updated: Feb 12, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Limb salvage and reconstruction following a zebra attack
Jacob T Carlson1, James C Yuen2, Matthew R Smeds3
1University of Arkansas for Medical Sciences, Department of General Surgery, 4301 W. Markham St., Little Rock, AR 72205, United States.
A severe zebra bite caused extensive arm trauma, including vascular and nerve damage. Multidisciplinary treatment involved revascularization, multiple debridements, advanced wound coverage, and antibiotics to manage infection and reconstruct the limb.
Area of Science:
- Trauma surgery
- Infectious disease
- Reconstructive surgery
Background:
- Animal bites, though rare, can lead to severe injuries and infections.
- Prompt and comprehensive management is crucial for limb salvage.
Observation:
- A healthy male sustained extensive injuries to his left upper extremity from a domestic zebra bite.
- Injuries included brachial artery devascularization, nerve damage, and soft tissue loss.
- Wound cultures revealed multiple microbes, including Rhodococcus spp.
Findings:
- Successful revascularization using a vein bypass graft was performed.
- Multiple irrigation and debridement procedures were necessary, with advanced techniques for wound coverage.
- A prolonged antibiotic course was administered, leading to negative wound cultures.
- Biceps reconstruction was achieved using a latissimus dorsi muscle transfer.
Implications:
- This case highlights the importance of a multidisciplinary approach in managing complex animal bite injuries.
- It demonstrates successful limb salvage and reconstruction following severe trauma from an unusual source.
- The management strategy underscores the need for vigilant infection control and tailored reconstructive techniques.
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