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Published on: August 15, 2025
Endoscopic full-thickness resection for gastrointestinal submucosal tumors
Ming-Yan Cai1, Francisco Martin Carreras-Presas2, Ping-Hong Zhou1
1Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital of Fudan University, Shanghai, China.
Endoscopic full-thickness resection (EFTR) offers a safe endoscopic method for removing deep gastrointestinal submucosal tumors (SMTs). This technique represents a significant advancement in minimally invasive therapeutic options.
Area of Science:
- Gastroenterology and Endoscopy
- Minimally Invasive Surgery
Background:
- Submucosal tumors (SMTs) in the gastrointestinal (GI) tract present challenges for complete resection.
- Traditional surgical methods can be invasive, leading to increased morbidity.
Purpose of the Study:
- To review the application of endoscopic full-thickness resection (EFTR) for gastrointestinal SMTs.
- To highlight technical aspects, indications, contraindications, and outcomes of EFTR.
Main Methods:
- Review of existing literature and case studies on EFTR for GI SMTs.
- Focus on the technical feasibility and safety profile of the EFTR procedure.
Main Results:
- EFTR enables safe, full-thickness resection of deep SMTs using flexible endoscopy.
- The technique integrates endoscopic and surgical principles for minimally invasive treatment.
- Outcomes related to EFTR efficacy and patient safety are discussed.
Conclusions:
- Endoscopic full-thickness resection (EFTR) is a promising technique for managing gastrointestinal submucosal tumors.
- EFTR represents a novel approach bridging endoscopy and surgery, paving the way for future therapeutic innovations.
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