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Related Experiment Videos

[Impetigo herpetiformis].

M Winzer1, H H Wolff

  • 1Klinik für Dermatologie und Venerologie, Medizinischen Universität zu Lübeck.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|February 1, 1988
PubMed
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Impetigo herpetiformis occurred in a patient on hormonal contraception and during pregnancies. Treatment with glucocorticosteroids and etretinate proved successful, suggesting therapeutic options for this rare condition.

Area of Science:

  • Dermatology
  • Obstetrics
  • Immunogenetics

Background:

  • Impetigo herpetiformis is a rare pustular psoriasis variant, often associated with pregnancy.
  • Hormonal factors may influence disease onset and severity.

Observation:

  • A 30-year-old patient experienced impetigo herpetiformis during hormonal contraception and two pregnancies.
  • A large splenic cyst was noted, potentially impacting disease course.
  • Diagnostic criteria for impetigo herpetiformis were reviewed.

Findings:

  • The patient's condition showed a recurrence linked to hormonal changes.
  • Association with the HLA-Cw 6 antigen was recognized.
  • Successful treatment was achieved with oral glucocorticosteroids and etretinate postpartum.

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Implications:

  • This case highlights the potential role of hormonal contraception in impetigo herpetiformis.
  • It underscores the importance of considering pregnancy as a trigger.
  • Effective therapeutic strategies involving systemic corticosteroids and retinoids are demonstrated.