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Updated: Feb 11, 2026

Localization of the Locus Coeruleus in the Mouse Brain
Published on: March 7, 2019
[Role of the Nucleolus in Rearrangements of the IGH Locus]
O V Iarovaia1,2,3,4, E S Ioudinkova1,2,3, S V Razin1,2,5
1Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334 Russia.
Abstract:
The review summarizes the results from a series of studies focusing on the role that the nucleolus plays in maturation of the IGH locus and the choice of its partner genes in leukemia-associated translocations. The role of nuclear compartmentalization and nuclear localization of translocated oncogenes in ectopic activation of their transcription is discussed.
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