[Discussion on relationship between "living alone with closed windows and doors" and depression]

"Living alone with closed windows and doors"was mentioned in the pathological manifestations of stomach meridian of foot-yangming in Neijing (The Inner Canon of Huangdi), which is similar to the symptoms of depression. Currently the treatment of depression is mostly based on"spirit being stored in five organs"theory, and little attention is paid on stomach meridian of foot-yangming. From the pathological manifestations of"living alone with closed windows and doors"in stomach meridian of foot-yangming, the relationship between stomach meridian and depression is discussed from ying-yang and qi-blood. In addition, the close relationship between the stomach meridian and qi-blood, qi movement of five organs, heart and brain is discussed to explore the mechanism of treating depression. In conclusion, the literature and modern research regarding treating depression from stomach meridian are summarized, hoping to provide more clinical methods for the treatment of depression.