Related Experiment Videos
[Advanced Parkinson's disease : indication for complex treatments].
Matthieu Béreau1, Emilie Tomkova2, André Zacharia1
1Service de neurologie, Département des neurosciences cliniques, HUG, 1211 Genève 14.
Revue Medicale Suisse
|April 28, 2018
Summary
Advanced Parkinson's disease (PD) involves severe motor and non-motor symptoms. For advanced stages, treatment options include deep brain stimulation (DBS), apomorphine infusion, or levodopa/carbidopa intestinal gel infusion.
Area of Science:
- Neurology
- Movement Disorders
Context:
- Advanced Parkinson's disease (PD) presents significant motor and non-motor complications.
- These complications substantially diminish patient autonomy and health-related quality of life.
Purpose:
- To outline therapeutic strategies for advanced Parkinson's disease.
- To identify advanced treatment options when standard dopaminergic therapy is insufficient.
Summary:
- Early PD management involves escalating dopaminergic treatment and levodopa dose adjustments.
- In advanced stages, standard therapies become inadequate, necessitating alternative interventions.
- Considered advanced therapies include deep brain stimulation (DBS), continuous subcutaneous apomorphine infusion, and continuous levodopa/carbidopa intestinal gel infusion.
Impact:
- Provides a concise overview of advanced treatment modalities for Parkinson's disease.
- Highlights the limitations of conventional therapy in later disease stages.
- Informs clinical decision-making for managing complex Parkinson's disease cases.