Related Experiment Video
Updated: Feb 11, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[What are the pharmacological options for treating resistant hypertension?]
N Martell-Claros1, M Abad-Cardiel1
1Unidad de Hipertensión, Servicio de Medicina Interna, Hospital Clínico San Carlos, Madrid, España; Instituto de Investigación Sanitaria, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, España.
Abstract:
When treating a patient with resistant hypertension therapy should be optimize in order to prescribe three antihypertensive drugs at full doses, being powerful drugs, having 24-hour coverage, and showing synergistic effects. Diuretic therapy is of special relevance. The fourth drug should be an aldosterone antagonists. In the case of intolerance, or when control is not achieved, drugs from other type of antihypertensive drugs should be, sometimes allowing adequate blood pressure control.
Related Concept Videos
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension V: Nursing Management
Resistivity
Resistance
Equivalent Resistance

