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Related Experiment Video

Updated: Feb 11, 2026

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models

Published on: December 8, 2023

Cytomegalovirus keratitis.

Samuel C Faith¹, Asad F Durrani, Vishal Jhanji

¹Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Current Opinion in Ophthalmology

|May 1, 2018

Summary

This summary is machine-generated.

Cytomegalovirus (CMV) keratitis can cause severe eye damage. Early diagnosis and treatment, using advanced techniques and clinical judgment, are crucial for managing this infection.

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Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

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Published on: July 6, 2013

Area of Science:

Ophthalmology
Infectious Diseases
Virology

Background:

Cytomegalovirus (CMV) keratitis is an uncommon but severe ocular manifestation of a widespread virus.
Prompt diagnosis and effective treatment are often delayed, contributing to significant visual morbidity.

Purpose of the Study:

To review recent literature on the epidemiology, pathophysiology, diagnosis, and therapy of CMV keratitis.
To highlight advancements in understanding and managing this ocular condition.

Main Methods:

Review of recently published scientific literature.
Analysis of current diagnostic approaches including PCR, advanced imaging, and genotyping.
Evaluation of therapeutic strategies.

Main Results:

Elucidation of classic and atypical presentations of CMV keratitis.
Advancements in diagnostic tools beyond PCR, incorporating imaging and genotyping.
Demonstration of the value of clinical expertise combined with modern technology for rapid diagnosis.

Conclusions:

Systemic ganciclovir remains the primary treatment for CMV keratitis.
Clinicians should suspect CMV keratitis in patients presenting with keratitis, anterior uveitis, and ocular hypertension.
Integrating novel diagnostic techniques with clinical findings is essential for accurate diagnosis, treatment, and monitoring.