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Bilateral optic neuropathy associated with amiodarone therapy.
1Neurology Service, John L. McClellan Memorial Veterans Hospital, Little Rock, Arkansas 72205.
Journal of Clinical Neuro-Ophthalmology
|March 1, 1988
Summary
Amiodarone, an antiarrhythmic drug, can cause vision loss. This case report details a patient who developed toxic optic neuropathy after starting amiodarone, highlighting potential risks.
Area of Science:
- Ophthalmology
- Cardiology
- Toxicology
Background:
- Amiodarone is a widely used antiarrhythmic medication.
- Previous reports have linked amiodarone to optic nerve issues like papillopathy and papilledema, often causing mild visual disturbances.
Observation:
- This study details a specific patient case.
- The patient initiated amiodarone therapy for an unspecified condition.
- Within four weeks of starting the medication, bilateral optic neuropathy was observed.
Findings:
- The patient experienced significant vision impairment in both eyes.
- Nine months post-initiation, visual acuity remained notably reduced (20/50 OD, 20/200 OS).
- The observed condition is consistent with amiodarone-induced toxic optic neuropathy.
Implications:
- This case adds to the evidence suggesting amiodarone can induce toxic optic neuropathy.
- Ophthalmologists and cardiologists should be aware of this potential adverse effect.
- Monitoring visual function in patients on amiodarone may be warranted.