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Updated: Feb 11, 2026

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
Published on: February 17, 2023
Dual defibrillation in patients with refractory ventricular fibrillation
Karim Hajjar1, Iskandar Berbari2, Chady El Tawil1
1Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Abstract:
In the setting of cardiac arrest, refractory ventricular fibrillation (VF) is difficult to manage, and mortality rates are high. Double sequential defibrillation (DSD) has been described in the literature as a successful means to terminate this malignant rhythm, after failure of traditional Advanced Cardiac Life Support (ACLS) measures. The authors herein present a case of refractory VF in a patient with cardiac arrest, on whom DSD was successful in reversion to sinus rhythm, and provide a thorough review of similar cases in the literature.
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