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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

1.8K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Anatomical Movements00:51

Anatomical Movements

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Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
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Intrinsically Disordered Proteins02:18

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Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
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The Movement of Organelles and Vesicles01:43

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In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
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Fluid Movement Between Compartments01:18

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The force applied by fluids against a surface, known as hydrostatic pressure, initiates the transfer of fluid among different compartments. Within our blood vessels, the blood's hydrostatic pressure is a result of the heart's pumping action. At the arteriolar end of capillaries, hydrostatic pressure (capillary blood pressure) exceeds the opposing colloid osmotic pressure created primarily by plasma proteins like albumin. This discrepancy in pressure propels plasma and nutrients from the...
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Movement Joints in Buildings01:27

Movement Joints in Buildings

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Movement joints in buildings are essential design elements that accommodate inevitable motions caused by various factors such as temperature changes, moisture content variations, and structural deflections. These motions, if not considered in design and construction, can lead to unsightly or dangerous damage. Movement joints are incorporated in different forms to manage these stresses and allow materials to move without causing distress.
The simplest type of movement joints, working joints, are...
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Related Experiment Video

Updated: Feb 11, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
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Autoimmune Movement Disorders in Children.

Coral M Stredny1, Jeff L Waugh1

  • 1Department of Neurology, Boston Children's Hospital, Boston, MA.

Seminars in Pediatric Neurology
|May 9, 2018
PubMed
Summary

Pediatric autoimmune neurologic disorders often present with movement disorders, aiding early diagnosis. Recognizing these abnormal movements is crucial for timely immunotherapy and improved outcomes in children.

Area of Science:

  • Pediatric Neurology
  • Autoimmune Disorders
  • Movement Disorders

Background:

  • Significant advances in identifying, characterizing, and treating pediatric autoimmune neurologic disorders.
  • Movement disorders are common presenting symptoms in these conditions.
  • Early diagnosis of autoimmune diseases or associated malignancies is facilitated by recognizing movement abnormalities.

Purpose of the Study:

  • To review the clinical characteristics, diagnosis, and treatment of movement disorders in pediatric autoimmune disorders.
  • To emphasize the importance of recognizing movement disorder patterns for early detection.
  • To highlight the role of immunotherapy in improving outcomes.

Main Methods:

  • Literature review of pediatric autoimmune neurologic disorders with movement abnormalities.

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  • Synthesis of clinical characteristics, diagnostic approaches, and treatment strategies.
  • Focus on the diagnostic utility of movement disorders.
  • Main Results:

    • Movement disorders are key indicators in many pediatric autoimmune neurologic conditions.
    • These symptoms can precede other signs, enabling earlier detection of underlying systemic diseases or cancers.
    • Recognition of specific movement patterns aids in timely diagnosis and intervention.

    Conclusions:

    • Early identification and treatment of movement disorders in pediatric autoimmune conditions are essential.
    • Immunotherapy can lead to improved prognoses.
    • Child neurologists must be adept at recognizing these movement patterns for effective patient management.