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Related Concept Videos

Imprinting01:22

Imprinting

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Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
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Genomic Imprinting and Inheritance02:30

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
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Plasticity00:58

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Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
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Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
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Plastic Behavior01:21

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A material's elastic behavior is characterized by the disappearance of stress once the load is removed, allowing the material to return to its original state. However, when stress surpasses the yield point, yielding commences, marking the onset of plastic deformation or permanent set. This change from elastic to plastic behavior is influenced by the peak stress value and the duration before the load is removed. An intriguing observation occurs when a specimen is loaded, unloaded, and...
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Plastic Deformations01:14

Plastic Deformations

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It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...
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Multiscale Structures Aggregated by Imprinted Nanofibers for Functional Surfaces
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Imprint stability and plasticity during development.

Sarah-Jayne Mackin1, Avinash Thakur1, Colum P Walsh2

  • 1Genomic Medicine Research GroupSchool of Biomedical Sciences, Ulster University, Northern Ireland, UK.

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|May 11, 2018
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Summary
This summary is machine-generated.

Genomic imprinting, where gene expression depends on parental origin, is increasingly studied in diverse species. New research highlights the critical role of imprint maintenance after implantation and explores its somatic reprogramming and conservation.

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Area of Science:

  • Genetics
  • Epigenetics
  • Genomic Imprinting

Background:

  • Genomic imprinting involves parent-of-origin-specific gene silencing.
  • Imprinting is crucial for mammalian development, influencing growth and body size.
  • Traditionally studied in mice and humans, imprinting research is expanding to other organisms.

Purpose of the Study:

  • To review current knowledge on genomic imprinting.
  • To discuss the importance of imprint maintenance post-implantation.
  • To explore somatic reprogramming, imprinted loci, and cross-species conservation.

Main Methods:

  • Review of recent scientific literature.
  • Analysis of emerging genomic interrogation techniques.
  • Survey of methods for genome-wide DNA methylation analysis.

Main Results:

  • Imprint maintenance after implantation is critical.
  • Imprinting effects are being investigated in a wider range of species.
  • New techniques facilitate broader genomic imprinting studies.

Conclusions:

  • Genomic imprinting is a dynamic epigenetic process with significant biological roles.
  • Further research is needed to understand somatic reprogramming and imprint conservation.
  • Advancements in genomic technologies are driving the field forward.