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Updated: Feb 10, 2026

3D Bioprinting of Murine Cortical Astrocytes for Engineering Neural-Like Tissue
Published on: July 16, 2021
3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
Soroosh Derakhshanfar1, Rene Mbeleck1, Kaige Xu1
1Department of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Abstract:
3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequisite toward advancing 3D printing applications in tissue engineering. Printability to improve fabrication process and cell encapsulation are two of the main factors to be considered in development of 3D bioprinting. Other important factors include but are not limited to printing fidelity, stability, crosslinking time, biocompatibility, cell encapsulation and proliferation, shear-thinning properties, and mechanical properties such as mechanical strength and elasticity. In this review, we recite recent promising advances in bioink development as well as bioprinting methods. Also, an effort has been made to include studies with diverse types of crosslinking methods such as photo, chemical and ultraviolet (UV). We also propose the challenges and future outlook of 3D bioprinting application in medical sciences and discuss the high performance bioinks.
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