Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension I: Introduction01:28

Hypertension I: Introduction

953
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
953
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

1.0K
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.0K
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

482
The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
482
Resistivity01:22

Resistivity

4.6K
When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.6K
Resistance01:19

Resistance

6.0K
When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
6.0K
RACE - Rapid Amplification of cDNA Ends02:35

RACE - Rapid Amplification of cDNA Ends

7.3K
Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific...
7.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peripheral artery disease in pseudoxanthoma elasticum: Walking capacity on the 6-minute walking test.

Vascular medicine (London, England)·2026
Same author

Arterial stiffness is related to a higher risk of cardiovascular events in patients with pseudoxanthoma elasticum (PXE).

Vascular medicine (London, England)·2026
Same author

Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension.

Global heart·2025
Same author

The TEMP-PREVENT trial: a study protocol for a randomized, double-blind, placebo-controlled clinical trial of etidronate for treatment in young adult patients with pseudoxanthoma elasticum.

Trials·2025
Same author

Cost-effectiveness of radiofrequency renal denervation for uncontrolled and resistant hypertension in The Netherlands.

Blood pressure·2025
Same author

Prevalence of cervical fibromuscular dysplasia among aneurysmal subarachnoid hemorrhage patients.

International journal of stroke : official journal of the International Stroke Society·2025

Related Experiment Video

Updated: Feb 10, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
07:35

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

13.3K

Endovascular Baroreflex Amplification for Resistant Hypertension.

Monique E A M van Kleef1, Mark C Bates2, Wilko Spiering3

  • 1Department of Vascular Medicine, University Medical Center Utrecht, Utrecht University, P.O. Box 85500, 3508, GA, Utrecht, The Netherlands.

Current Hypertension Reports
|May 11, 2018
PubMed
Summary

Carotid baroreceptors are key to managing hypertension. Device-based therapies like baroreflex activation therapy (BAT) and endovascular baroreflex amplification (EBA) show promise for controlling blood pressure by targeting this system.

Keywords:
BaroreceptorBaroreflex activation therapyDevice-based antihypertensive therapyEndovascular baroreflex amplificationResistant hypertensionSympathetic activity

More Related Videos

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

5.9K
Simulator Training for Endovascular Neurosurgery
08:08

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

4.2K

Related Experiment Videos

Last Updated: Feb 10, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
07:35

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

13.3K
Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

5.9K
Simulator Training for Endovascular Neurosurgery
08:08

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

4.2K

Area of Science:

  • Cardiovascular medicine
  • Hypertension research
  • Neuroscience

Background:

  • Hypertension is often linked to an imbalanced sympathetic nervous system.
  • Carotid baroreceptors are crucial for maintaining adrenergic balance and represent a potential therapeutic target.

Purpose of the Study:

  • To review the baroreceptor's role in hypertension.
  • To examine device-based therapies targeting the baroreflex.
  • To explore the potential of endovascular baroreflex amplification (EBA).

Main Methods:

  • Review of existing literature on baroreflex therapies.
  • Analysis of baroreflex activation therapy (BAT) and EBA mechanisms.
  • Examination of clinical trial data and study outcomes.

Main Results:

  • Two main strategies, BAT and EBA, enhance carotid baroreceptor activity.
  • BAT demonstrates significant sympathetic inhibition and blood pressure reduction, supporting its use in resistant hypertension.
  • EBA is a less invasive approach with promising initial results.

Conclusions:

  • Device-based therapies targeting the baroreflex offer new avenues for hypertension management.
  • Further randomized controlled trials are necessary to validate EBA's efficacy, safety, and identify optimal patient candidates.