Related Experiment Video
Updated: Feb 10, 2026

Ballistic Labeling of Pyramidal Neurons in Brain Slices and in Primary Cell Culture
Published on: April 2, 2020
Establishing the kinetics of ballistic-to-diffusive transition using directional statistics
Pai Liu1, William R Heinson1, Benjamin J Sumlin1
1Center for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, Missouri 63130, USA.
Abstract:
We establish the kinetics of ballistic-to-diffusive (BD) transition observed in two-dimensional random walk using directional statistics. Directional correlation is parameterized using the walker's turning angle distribution, which follows the commonly adopted wrapped Cauchy distribution (WCD) function. During the BD transition, the concentration factor (ρ) governing the WCD shape is observed to decrease from its initial value. We next analytically derive the relationship between effective ρ and time, which essentially quantifies the BD transition rate. The prediction of our kinetic expression agrees well with the empirical datasets obtained from correlated random walk simulation. We further connect our formulation with the conventionally used scaling relationship between the walker's mean-square displacement and time.
Related Concept Videos
Passive Diffusion: Overview and Kinetics
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
Statistical Significance
Phase Transitions: Sublimation and Deposition
Phase Transitions
Diffusion
Phase Transitions: Melting and Freezing

