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Updated: Feb 10, 2026

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An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
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Company Profile: Multiple Myeloma Research Foundation
1Multiple Myeloma Research Foundation (MMRF) & the Multiple Myeloma Research Consortium (MMRC), Norwalk, CT, USA. giustik@themmrf.org.
Personalized Medicine
|May 16, 2018
Summary
The Multiple Myeloma Research Foundation
Area of Science:
- Oncology
- Genetics
- Pharmacology
Background:
- Nonprofit organizations are increasingly vital in drug development.
- Multiple myeloma treatment responses vary significantly based on molecular profiles.
- Personalized medicine offers potential for improved patient outcomes.
Purpose of the Study:
- To advance personalized treatment approaches for multiple myeloma.
- To investigate the relationship between genetic profiles and treatment response.
- To drive innovation in multiple myeloma therapy through research.
Main Methods:
- The Multiple Myeloma Research Foundation (MMRF) initiated the CoMMpass study.
- Collection and analysis of tissue samples and genetic data from ~1000 patients.
- Longitudinal study design over 5 years to capture comprehensive data.
Main Results:
- Data collection and analysis are ongoing.
- The study aims to identify key genetic markers influencing treatment efficacy.
- Findings will inform the development of tailored therapies.
Conclusions:
- The CoMMpass study is crucial for advancing personalized medicine in multiple myeloma.
- Understanding molecular profiles will enable more predictable and effective treatments.
- This research supports the MMRF's vision for individualized patient care.
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