Related Experiment Video
Updated: Feb 10, 2026

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Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
Published on: January 29, 2020
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Facial involvement in progressive macular hypomelanosis
Krystle Wang1, Yomna Nassef1, Joya Sahu1
1Department of Dermatology and Cutaneous Biology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Cutis
|May 16, 2018
Summary
Progressive macular hypomelanosis (PMH), typically affecting the trunk, can also appear on the face. This study highlights PMH as a key consideration for facial hypopigmentation.
Area of Science:
- Dermatology
- Medical Science
Background:
- Progressive macular hypopigmentation (PMH) is a recognized skin condition.
- Historically, PMH has been characterized by its distribution primarily on the trunk.
Observation:
- This report details four adult cases of PMH.
- A notable feature in these cases was the involvement of the face.
Findings:
- The diagnosis of PMH was confirmed in all four patients.
- Other potential causes of hypopigmented skin conditions were systematically excluded.
Implications:
- This study expands the known clinical presentation of PMH.
- Healthcare providers should include PMH in the differential diagnosis for facial hypopigmented lesions.
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