Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adult Stem Cells01:33

Adult Stem Cells

33.9K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
33.9K
Accelerators01:17

Accelerators

292
Accelerators in concrete serve as admixtures to speed up the hardening process, enabling the concrete to achieve early strength faster. Although accelerators do not necessarily impact the time it takes concrete to set, they reduce this time in practice. A common accelerator is calcium chloride, which is particularly useful for hastening early strength development in cold weather or for rapid repair jobs that require quick heat generation after mixing.
The effectiveness of calcium chloride can...
292
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.6K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.6K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.1K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.1K
Average Acceleration01:30

Average Acceleration

14.3K
The importance of understanding acceleration spans our day-to-day experiences, as well as the vast reaches of outer space and the tiny world of subatomic physics. In everyday conversation, to accelerate means to speed up. For instance, we are familiar with the acceleration of our car; the harder we apply our foot to the gas pedal, the faster we accelerate. The greater the acceleration, the greater the change in velocity over a given time. Acceleration is widely seen in experimental physics. In...
14.3K
Instantaneous Acceleration01:16

Instantaneous Acceleration

23.3K
Acceleration is in the direction of the change in velocity, but it is not always in the direction of motion. When an object slows down, its acceleration is opposite to the direction of its motion. Although commonly referred to as deceleration, this causes confusion in our analysis as deceleration is not a vector, and does not point to a specific direction with respect to a coordinate system. Therefore, the term deceleration is not used. For example, when a subway train slows down, it...
23.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipid Network Crosslinked Hydrogels: Controlling Material Dynamics Across Multiple Length Scales Through Lipid Movement.

bioRxiv : the preprint server for biology·2026
Same author

15-PGDH inhibition promotes muscle repair and strength recovery during GLP-1 receptor agonist-induced weight loss.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

15-PGDH Inhibition Overcomes Muscle Regenerative Deficit Seen With GLP1-Receptor Agonist-Induced Weight Loss.

bioRxiv : the preprint server for biology·2026
Same author

Physiological Buffer Selection Alters the Mechanics of Hydrogels with Hydrazone Cross-Links.

Biomacromolecules·2026
Same author

Stress relaxation timescale and hydrogel network connectivity regulate neural progenitor cell stemness and differentiation.

Journal of materials chemistry. B·2026
Same author

A diffusion-based 3D printing strategy to fabricate self-supporting, perfusable networks.

BMC methods·2026

Related Experiment Video

Updated: Feb 10, 2026

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
09:19

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Published on: January 4, 2015

11.2K

Bioengineering strategies to accelerate stem cell therapeutics.

Christopher M Madl1, Sarah C Heilshorn2, Helen M Blau3

  • 1Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.

Nature
|May 18, 2018
PubMed
Summary

Bioengineering advances, including biomaterials and 3D hydrogels, are unlocking the regenerative potential of stem cells for new therapies and drug discovery. These technologies promise to overcome current challenges in regenerative medicine.

More Related Videos

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
09:01

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles

Published on: September 27, 2013

11.6K
Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

Published on: June 20, 2015

20.2K

Related Experiment Videos

Last Updated: Feb 10, 2026

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
09:19

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Published on: January 4, 2015

11.2K
Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
09:01

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles

Published on: September 27, 2013

11.6K
Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

Published on: June 20, 2015

20.2K

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Stem Cell Biology

Background:

  • Stem cells possess significant regenerative potential, yet clinical applications remain limited.
  • Current limitations hinder the translation of stem cell therapies into widespread patient use.

Purpose of the Study:

  • To explore how bioengineering technologies can overcome bottlenecks in stem cell therapy.
  • To highlight the role of biomaterials and advanced culture platforms in advancing regenerative medicine.

Main Methods:

  • Utilizing biomaterials with tunable mechanical and biochemical properties for stem cell culture.
  • Employing three-dimensional (3D) hydrogel platforms for organoid development and drug screening.

Main Results:

  • Biomaterials enhance stem cell function, survival, and guide tissue regeneration.
  • 3D hydrogel platforms facilitate patient-specific organoid generation and drug discovery.
  • These approaches stimulate endogenous tissue-specific stem cells.

Conclusions:

  • Bioengineering technologies are crucial for advancing stem cell therapies.
  • These innovations are poised to revolutionize regenerative medicine by enabling new treatments and drug discovery.
  • The development of advanced biomaterials and culture systems is key to realizing the full potential of stem cells.