Related Experiment Video
Updated: Feb 10, 2026

In Vitro Cellular Activity Evaluation of the Nanoemulsion Vaccine Adjuvant Ophiopogonin D
Published on: December 9, 2022
The Canadian Immunization Monitoring Program, ACTive (IMPACT): Active surveillance for vaccine adverse events and
J A Bettinger1, S A Halperin2, W Vaudry3
1Vaccine Evaluation Center, BC Children's Hospital and the University of British Columbia, Vancouver, BC.
Abstract:
For almost 25 years the Canadian Immunization Monitoring Program, ACTive (IMPACT) has been conducting active surveillance for severe adverse events following immunization (AEFIs) and vaccine-preventable diseases in children. The network, which consists of volunteer paediatric infectious diseases investigators at 12 tertiary care paediatric hospitals, is an important component of Canada's AEFI monitoring. The network employs nurses at each of the sites to search for and report possible AEFIs to local, provincial and national public health authorities. The active nature of the surveillance ensures a high level of vigilance for severe AEFIs in children.
Related Concept Videos
Vaccinations
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Active versus Passive Immunity
Active Immunity
Active immunity refers to the resistance one develops...
Principles of Disease Surveillance
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
Co-activators and Co-repressors

