[Inflammatory myofibroblastic tumor of the larynx: a case report]

Inflammatory myofibroblastic tumor(IMT) is a kind of mesenchymal tumor. It commonly occurs in the lungs. It rarely occurs in head and neck. A 81 years old man presented to the otolaryngology clinic with hoarseness for 40 days. Electron laryngoscopy revealed a right vocal mass(10 mm×10 mm). Under MRI, the lesion in right vocal fold was shown as soft tissue mass with unclear border, and had a slightly hyperintense on T1 weighted images and slightly hyperintense on T2 weighted images.The histopathological result showed that fibrous connective tissue was infiltrated by various kinds of inflammatory cells including lymphocytes and plasma cells with marked atypia and mitoses, and angiogenesis was also found in the lesion. Immunochemistry showed that smooth muscle actin(SMA) (+), Ki 67(40%), S 100(-), Desmin(-), CD34(-),CK(-), and anaplastic lymphoma kinase protein(-). The histopathological result suggested that the lesion was inflammatory myofibroblastic tumor.