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Updated: Feb 10, 2026

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Foveal Avascular Zone Area Analysis in Macular Hole Before and After Surgery Using Optical Coherence Tomography
Background And Objective:
To analyze the foveal avascular zone (FAZ) area in superficial and deep retinal layers in patients with macular hole (MH) before and after surgery.
Patients And Methods:
The authors studied 14 patients with unilateral MH. They examined a 3 mm × 3 mm area at the fovea before and 6 months after surgery using spectral-domain optical coherence tomography angiography.
Results:
In eyes affected by MH, the mean preoperative superficial FAZ (0.45 ± 0.09 mm2) and deep FAZ (0.79 ± 0.39 mm2) were significantly larger than the postoperative superficial FAZ (0.25 ± 0.09 mm2) and deep FAZ (0.31 ± 0.12 mm2), respectively (P < .001). The mean preoperative superficial FAZ of the affected eyes was the same as that of control eyes (0.41 ± 0.10 mm2) (P = .23), but postoperative superficial FAZ was smaller than that of control eyes (P < .001). The mean preoperative deep FAZ was larger (0.48 ± 0.11 mm2) (P = .019), but mean postoperative deep FAZ was smaller than that of control eyes (P < .001).
Conclusions:
The authors revealed preoperative deep FAZ areas were more enlarged centrifugally than preoperative superficial FAZ in MH. Both postoperative superficial and deep FAZ showed more centripetal contraction than those of the preoperative period. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:329-335.].
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