Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vision01:24

Vision

60.3K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
60.3K
Lifecycle of Erythrocytes01:22

Lifecycle of Erythrocytes

5.4K
Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups....
5.4K
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

2.3K
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
2.3K
Plastic Deformations01:19

Plastic Deformations

474
Plastic deformation represents a fundamental concept in materials science, which explains the irreversible change in the shape of a material when it experiences stress beyond its elastic capability. This phenomenon is important in structural engineering, especially in designing and analyzing cantilever beams—structures that are securely fixed at one end and bear loads at the opposite end. When these beams are subjected to loads within their elastic range, they will return to their...
474
Plastic Deformations01:14

Plastic Deformations

473
It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...
473
Color Vision01:24

Color Vision

1.5K
Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LOXL4 drives radiotherapy resistance and immunosuppression in glioma by targeting SOCS3 for degradation to activate STAT3 signaling.

International immunopharmacology·2026
Same author

CSF1R inhibitors mitigate CDK4/6 inhibitor-induced immunosuppression to increase antitumor immunity in HR+/HER2- breast cancer.

Oncogene·2026
Same author

Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management.

MedComm·2026
Same author

Thermosensitive hydrogel-enhanced RPA-CRISPR/Cas12a biosensor for ultrasensitive detection of methylated loci in breast cancer ctDNA.

Analytica chimica acta·2026
Same author

α-lipoic acid nanoparticles functionalized with RVG29 peptide attenuate seizure-induced neurotoxicity by restoring mitochondrial homeostasis via the PINK1/Parkin pathway.

Free radical biology & medicine·2025
Same author

iRGD-engineered exosomes mediate siMYC delivery for effective tumor suppression in triple-negative breast cancer.

Nanoscale·2025

Related Experiment Video

Updated: Feb 10, 2026

A Microfluidic Technique to Probe Cell Deformability
09:47

A Microfluidic Technique to Probe Cell Deformability

Published on: September 3, 2014

11.8K

[The Erythrocyte Deformability Measuring System Based on Microlfuidic and Machine Vision].

Jianxun Hou, Sehyun Xhin

    Zhongguo Yi Liao Qi Xie Za Zhi = Chinese Journal of Medical Instrumentation
    |May 19, 2018
    PubMed
    Summary

    This study presents a new microfluidic and machine vision system for measuring erythrocyte deformability. The improved system accurately assesses red blood cell flexibility without laborious washing steps.

    More Related Videos

    Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
    09:12

    Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

    Published on: January 12, 2018

    15.5K
    Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry
    07:20

    Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry

    Published on: May 19, 2020

    7.7K

    Related Experiment Videos

    Last Updated: Feb 10, 2026

    A Microfluidic Technique to Probe Cell Deformability
    09:47

    A Microfluidic Technique to Probe Cell Deformability

    Published on: September 3, 2014

    11.8K
    Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
    09:12

    Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

    Published on: January 12, 2018

    15.5K
    Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry
    07:20

    Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry

    Published on: May 19, 2020

    7.7K

    Area of Science:

    • Hematology
    • Biomedical Engineering
    • Microfluidics

    Background:

    • Erythrocyte deformability is crucial and depends on cell membrane and cytoplasm composition.
    • Existing methods for measuring erythrocyte deformability are often labor-intensive and time-consuming due to required washing steps.

    Purpose of the Study:

    • To introduce an improved, rapid system for measuring erythrocyte deformability.
    • To validate the accuracy and repeatability of the new system against a conventional method.

    Main Methods:

    • Development of a novel measuring system integrating microfluidics and machine vision (RSD).
    • Utilized disposable microfluidic channels and a conventional laser-diffraction technique.
    • Compared erythrocyte deformability measurements (Elongation Index) with a standard ektacytometer (LORCA).

    Main Results:

    • The novel RSD system successfully determined erythrocyte deformability.
    • Measurements of the Elongation Index (EI) by RSD showed excellent agreement with those from LORCA.
    • The system eliminates the need for pre-measurement washing, saving time and labor.

    Conclusions:

    • The microfluidic and machine vision-based RSD system offers an accurate and repeatable method for assessing erythrocyte deformability.
    • This improved system provides a more efficient alternative to conventional techniques, simplifying red blood cell analysis.