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Updated: Feb 10, 2026

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring
Published on: November 29, 2024
Perspectives for applying the additional study methods for diagnostics optimization of postoperative hypertrophic
David S Avetikov1, Olha P Bukhanchenko1, Ihor O Ivanytskyi1
1Higher State Educational Establishment Of Ukraine «Ukrainian Medical Stomatological Academy», Poltava, Ukraine.
Objective:
Introduction: The issue of improving the quality of diagnosis, prevention and treatment of patients with pathological scarring of the head and neck is being actively developed throughout the world. The aim of the research is to improve diagnostics of hypertrophic scars of the head and neck through the establishment of structural features of scar-modified tissues using RGB-system and ultrasound examination.
Patients And Methods:
Materials and methods: In this study, 60 patients with hypertrophic scars of the head and neck were examined. Under our supervision, there were patients in whom the type of scar was previously confirmed clinically and morphologically.
Results:
Results: Based on the optical analysis of the obtained images, it can be concluded that hypertrophic scars are well visualized and are different from intact skin. We created a standardized table of numerical values for distribution of color components in the RGB system. Analyzing the data as for the numerical differences in terms of echogenicity of hypertrophic scars, we found that the echogenicity changes in the area of medial and lateral edges of the scar had significant differences.
Conclusion:
Conclusions: A comprehensive examination of patients with hypertrophic scarring of the head and neck, which implies the mandatory use of RGB-visualization and ultrasound examination, enables us to differentiate the type of scar tissue. The described comprehensive approach to examination of patients with scarring will provide the optimal choice of methods for treatment.
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