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Recent Advances in Nanosuspension Technology for Drug Delivery
Daisy Arora1,2, Bharat Khurana1,3, Goutam Rath1
1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab), India.
Background:
Discovery and development of BCS class 1 drugs through high throughput screening is one of the biggest challenge faced by formulation scientist.
Methods:
There are a number of approaches that have been exploited to enhance the solubility and permeability of drugs. Among them, development of nanosuspension has offered several benefits. These techniques may increase effective surface area due to nanonization of drug particles and further increases saturation solubility and dissolution properties for improved bioavailability. Various development methods are patented which are cost effective and easy to scale up.
Conclusion:
Several unique features of nanosuspension make it a versatile delivery system for different routes of administration including oral, dermal, ocular, parenteral and pulmonary. The present review is focused on preparatory techniques and formulation considerations of nanosuspension. Brief information about evaluation parameters, applications of nanosuspension in drug delivery and patented and marketed products available is also discussed.
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Overview of Advanced Functional Groups
Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.

