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[Clinical analysis of 5 invasive fungal rhinosinusitis cases]

L Yang1, N Li1

  • 1Department of Otorhinolaryngology Head and Neck Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, China.

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
|May 26, 2018
PubMed

Insights

Invasive fungal rhinosinusitis (IFRS) requires comprehensive management. Early diagnosis and a combination of surgery with antifungal therapy can improve patient outcomes.

Area of Science:

  • Otolaryngology
  • Mycology
  • Infectious Diseases

Background:

  • Invasive fungal rhinosinusitis (IFRS) is a severe infection often seen in immunocompromised patients.
  • Risk factors include diabetes mellitus, leukemia, and chemotherapy, predisposing individuals to fungal invasion of the sinuses.

Observation:

  • A study of five IFRS patients revealed common comorbidities like diabetes and a history of chemotherapy.
  • All patients underwent surgical intervention combined with antifungal treatment.

Findings:

  • Follow-up for 1 to 3 years showed a 60% clinical cure rate (3 out of 5 patients).
  • Mortality occurred in two patients due to disease relapse and exacerbation, highlighting the aggressive nature of IFRS.

Implications:

  • Integrated treatment strategies, including surgery and antifungal medications, are crucial for managing IFRS.
  • Multifaceted diagnostic and therapeutic approaches are necessary for improving survival rates in invasive fungal rhinosinusitis.
Keywords:
fungisinusitissurgical procedures, operative

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