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Updated: Feb 10, 2026

Analysis of Human Natural Killer Cell Metabolism
Published on: June 22, 2020
[Extranodal Natural Killer/T-Cell Lymphoma, nasal-type with primary cutaneous involvement. A case report]
Marcos Silva-Feistner1, María Jesús Rojas-Lechuga2, Elena Ortiz1
1Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile.
Introduction:
Extranodal natural killer/T-cell lymphoma (NK/T), nasal type, is an infrequent neoplasm with a high lethality, characterized by bone destruction around the sinus, nasal septum or obstruction of the airway. Also, may be primary skin involvement, airway and other organs. Objecti ve: Submit a rare condition in the pediatric population, in order to facilitate the diagnostic suspicion and quick recognition from specialists.
Case Report:
a 14-year-old girl, who presented arm and leg lesions, painless, suggestive of subcutaneous panniculitis, which evolve to ulcerated purple maculae. Skin biopsy showed lesion compatible with NK/T lymphoma, nasal type. She was referred to pedia tric oncology, where she received chemotherapy treatment. Despite medical efforts, the patient died eight months after due to a serious pulmonary infection secondary to immunosuppression. Conclu sions: Extranodal NK/T-cell lymphoma, nasal type, is a rare neoplasm that behaves aggressively, with high mortality without treatment, therefore, its recognition has a high importance for early diagnosis and prompt referral to Hematology-Oncology.
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