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Published on: September 27, 2017
[Bleomycin-induced Flagellated dermatitis: A case report].
Jonathan Stevens G1, María Teresa Dossi C2, Gianna Muñoz M3
1Departamento de Dermatología, Facultad de Medicina, Universidad de Chile, Chile.
Flagellated dermatitis, a rare skin condition, can occur after bleomycin chemotherapy. Prompt diagnosis and topical corticosteroid treatment led to a good outcome in a pediatric case.
Area of Science:
- Dermatology
- Pediatric Oncology
- Clinical Case Study
Background:
- Flagellated dermatitis is an uncommon skin reaction associated with bleomycin chemotherapy.
- Characterized by linear, erythematous to hyperpigmented maculae resembling a flagellar pattern on the trunk and extremities.
- Typically self-limiting, with treatment ranging from observation to topical or oral corticosteroids.
Observation:
- A case report of an 8-year-old female treated for a central nervous system neoplasm with the PEB protocol, including bleomycin.
- Developed intermittent pruritus and characteristic flagellated dermatitis lesions on the abdomen and back two days post-bleomycin administration.
- Presented with erythematous and pigmented maculae in a linear, flagellated distribution with excoriations.
Findings:
- Topical mild-potency corticosteroids were administered for ten days.
- The patient showed a satisfactory clinical response to the topical corticosteroid treatment.
- The skin lesions resolved with appropriate management.
Implications:
- High diagnostic suspicion is crucial for pediatric patients with a history of bleomycin exposure presenting with characteristic skin lesions.
- Early identification and management can allow for continued chemotherapy and prevent complications.
- This case highlights the importance of recognizing bleomycin-induced flagellated dermatitis in pediatric oncology.
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